Hypothyroidism Patient Scenarios

Please see the additional Important Safety Information at the end of this video, including the BOXED WARNING regarding inappropriate treatment for obesity or for weight loss. Levothroid is used for hashimoto’s disease, hypothyroidism, after thyroid removal, myxedema coma … Biotin supplementation is known to interfere with thyroid hormone immunoassays that are based on a biotin and streptavidin interaction, which may result in erroneous thyroid hormone test results.

USE IN SPECIFIC POPULATIONS

DAW codes are codes a pharmacy uses when filling your patient’s prescription. DAW-1 indicates that substitution is not allowed, based on the prescriber’s preference, and ensures your patient will receive the treatment you prescribe. It also helps your patient pay the lowest possible price for the product you write if it is billed through insurance. That’s because substitutions can be made at the pharmacy if the prescription is not properly protected with the Dispense as Written (DAW) state-specific language. Some key points that I discuss with the patients during appointments are, one, is that this is an open conversation.

Do not administer in foods that decrease absorption of SYNTHROID, such as soybean-based infant formula see Drug Interactions (7.9). The signs and symptoms of overdosage are those of hyperthyroidism see WARNINGS AND PRECAUTIONS and Adverse Reactions. Seizures occurred in a 3-yearold child ingesting 3.6 mg of levothyroxine. Titrate the dose of SYNTHROID carefully and monitor response to titration to avoid these effects see DOSAGE AND ADMINISTRATION.

Assess compliance, dose of medication administered, and method of administration prior to increasing the dose of SYNTHROID see Warnings and Precautions (5.1) and Use in Specific Populations (8.4). Assess compliance, dose of medication administered, and method of administration prior to increasing the dose of SYNTHROID see WARNINGS AND PRECAUTIONS and Use In Specific Populations. Circulating thyroid hormones are greater than 99% bound to plasma proteins, including thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), and albumin (TBA), whose capacities and affinities vary for each hormone.

Recently diagnosed patient*

Carefully monitor glycemic control, especially when thyroid therapy is started, changed, or discontinued see WARNINGS AND PRECAUTIONS. Medicines that interact with Synthroid may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Synthroid. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does.

Patient resources

The recommended starting daily dosage of SYNTHROID in adults with primary, secondary, or tertiary hypothyroidism is based on age and comorbid cardiac conditions, as described in Table 1. For patients at risk of atrial fibrillation or patients with underlying cardiac disease, start with a lower dosage and titrate the dosage more slowly to avoid exacerbation of cardiac symptoms. Dosage titration is based on serum TSH or free-T4 see Dosage and Administration (2.2). Dosage titration is based on serum TSH or free-T4 see Important Considerations For Dosing. In adult patients with primary hypothyroidism, monitor serum TSH levels after an interval of 6 to 8 weeks after any change in dosage.

Levothyroxine injection is used in adults to treat myxedema coma. This is a key issue for synthroid components some of the elemental things like calcium and iron, that can interfere with thyroid hormone absorption and thus should be taken approximately 4 hours apart. There are certain foods that can interfere with the way SYNTHROID works, particularly we think about high-fiber foods that can interact with the absorption of thyroid medications. There are also certain vitamins and supplements that can interfere with the absorption of SYNTHROID. They can have changes in the female hormone status, either going on or off a birth control pill, going through menopause.

• One is that the peak therapeutic effect of levothyroxine at a given dose may not be obtained for 4-6 weeks after medication is ingested.
• Another group is those that have underlying cardiac disease or are at risk for atrial fibrillation.
• Initiate SYNTHROID therapy in this population at lower doses than those recommended in younger individuals or in patients without cardiac disease see Dosage and Administration (2.3) and Use in Specific Populations (8.5).
• Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
• Dangerous side effects or death can occur from the misuse of this medicine, especially if you are taking any other weight-loss medications or appetite suppressants.

A key part for the patients is to make sure that they’re getting the brand-name SYNTHROID that we have prescribed. And, as a practicing thyroid specialist, I have extensive clinical experience with using this medication. In addition to testing TSH, sometimes it may be important to run other labs such as a free T4, in addition to the TSH, to ensure you have accurate dosing in the medication.

And in many cases, to also pop the top off the bottle while they are at the pharmacy counter and look at the pills and make sure they have SYNTHROID embossed on those tablets. In order for Synthroid to be effective, it should always be taken the same way every day. This is important because the amount of medicine you need is very precise. And even the way you take Synthroid can affect how much medicine your body is getting. It’s important to always take your medication exactly as your doctor prescribed. Synthroid works best if you take it on an empty stomach, 30 to 60 minutes before breakfast.

Jennifer is a 32-year-old woman in her first trimester of pregnancy with

Speak to your doctor about how drug interactions should be managed. If you become pregnant while taking Synthroid, do not stop taking the medicine without your doctor’s advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. The signs and symptoms of overdosage are those of hyperthyroidism see Warnings and Precautions (5) and Adverse Reactions (6). Seizures occurred in a 3-year-old child ingesting 3.6 mg of levothyroxine.